| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cca | glnE | plu3972 | plu3969 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | 0.437 |
| cca | plu3970 | plu3972 | plu3970 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | 0.449 |
| cca | plu3971 | plu3972 | plu3971 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | SH3b domain-containing protein; Unnamed protein product; Similar to putative exported protein YgiM of Escherichia coli. | 0.890 |
| cca | rfaE | plu3972 | plu3968 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.447 |
| glnE | cca | plu3969 | plu3972 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.437 |
| glnE | plu3970 | plu3969 | plu3970 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | 0.791 |
| glnE | plu3971 | plu3969 | plu3971 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | SH3b domain-containing protein; Unnamed protein product; Similar to putative exported protein YgiM of Escherichia coli. | 0.510 |
| glnE | rfaE | plu3969 | plu3968 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.684 |
| plu2870 | plu3094 | plu2870 | plu3094 | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | 0.696 |
| plu2870 | plu3970 | plu2870 | plu3970 | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | 0.427 |
| plu2870 | uspE | plu2870 | plu2178 | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | Universal stress protein E; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.432 |
| plu2870 | yihI | plu2870 | plu0229 | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | Der GTPase-activating protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.736 |
| plu3094 | plu2870 | plu3094 | plu2870 | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | 0.696 |
| plu3094 | plu3970 | plu3094 | plu3970 | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | 0.497 |
| plu3094 | uspE | plu3094 | plu2178 | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | Universal stress protein E; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.716 |
| plu3094 | yihI | plu3094 | plu0229 | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | Der GTPase-activating protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.789 |
| plu3970 | cca | plu3970 | plu3972 | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.449 |
| plu3970 | glnE | plu3970 | plu3969 | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | 0.791 |
| plu3970 | plu2870 | plu3970 | plu2870 | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | Unnamed protein product; Highly similar to 37 kDa nucleoid-associated protein YejK of Escherichia coli. | 0.427 |
| plu3970 | plu3094 | plu3970 | plu3094 | CYTH domain-containing protein; Unnamed protein product; Similar to unknown protein YgiF of Escherichia coli. | UPF0208 membrane protein plu3094; Unnamed protein product; Similar to unknown protein YfbV of Escherichia coli. | 0.497 |
