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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degSProtease DegS; Truncated gene, similar to virulence-associated protein. (352 aa)    
Predicted Functional Partners:
rseA
Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...]
  
 
 0.846
ecfE
Protease EcfE.
 
  
 0.773
plu4457
AAA domain-containing protein; Truncated gene. Some similarities with the N-terminal region of unknown protein.
    
 0.724
ptrA
Protease III precursor (pitrilysin); 3.8; Belongs to the peptidase M16 family.
  
 
 0.700
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
 0.629
plu0306
Unnamed protein product; Similar to unknown protein YhjJ precursor of Escherichia coli.
  
  
 0.580
glpK
Glycerol kinase (ATP:glycerol 3-phosphotransferase) (glycerokinase) (GK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.535
plu4291
Unnamed protein product; Unknown protein. Putative secreted protein.
      
 0.520
bvgS
Virulence sensor protein BvgS precursor.
  
  
 0.513
arcB
Aerobic respiration control sensor protein.
  
  
 0.504
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.