STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (480 aa)    
Predicted Functional Partners:
plu3311
Unnamed protein product; Highly similar to putative 2-component transcriptional regulator YfhA of Escherichia coli.
 
  
 0.959
ptsN
Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component).
 
  
 0.945
plu3313
Unnamed protein product; Highly similar to putative sensor-like histidine kinase (two-component sensor protein kinase) YfhK of Escherichia coli.
     
 0.903
plu1233
Unnamed protein product; Similar to C-terminal region of formate hydrogenlyase transcriptional activator.
 
   
 0.896
plu4042
Unnamed protein product; Highly similar to probable sigma(54) modulation protein YhbH of Escherichia coli.
  
  
 0.890
rpoZ
DNA-directed RNA polymerase omega chain (transcriptase omega chain) (RNA polymerase omega subunit); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.846
rpoB
RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.842
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.825
glnG
Nitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
   
 0.816
plu3798
Sigma-54 factor interaction domain-containing protein; Unnamed protein product; Similar to the central region of response regulator of AtoC, ornithine/arginine decarboxylase inhibitor (ornithine decarboxylase antizyme).
 
   
 0.816
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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