STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsNNitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component). (155 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein NPr (nitrogen related HPr).
 
 
 0.987
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.886
rapZ
RNase adapter protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.873
fruA
PTS system, fructose-specific IIBC component.
 
  
 0.864
plu4042
Unnamed protein product; Highly similar to probable sigma(54) modulation protein YhbH of Escherichia coli.
  
  
 0.850
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.792
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.775
ptsP
Phosphoenolpyruvate-protein phosphotransferase PtsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr); Belongs to the PEP-utilizing enzyme family.
  
   
 0.773
fruB
PTS system, fructose-specific IIA/FPr component.
 
  
 0.771
plu1266
Unnamed protein product; Highly similar to probable sigma-54 modulation protein YfiA of Escherichia coli.
  
  
 0.689
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.