Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsNNitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component). (155 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein NPr (nitrogen related HPr).
 
 
 0.992
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.945
rapZ
RNase adapter protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.918
fruA
PTS system, fructose-specific IIBC component.
 
  
 0.916
plu4042
Unnamed protein product; Highly similar to probable sigma(54) modulation protein YhbH of Escherichia coli.
  
  
 0.913
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.848
ptsP
Phosphoenolpyruvate-protein phosphotransferase PtsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr); Belongs to the PEP-utilizing enzyme family.
  
   
 0.840
fruB
PTS system, fructose-specific IIA/FPr component.
 
  
 0.788
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.750
plu1266
Unnamed protein product; Highly similar to probable sigma-54 modulation protein YfiA of Escherichia coli.
  
  
 0.736
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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