STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsOPhosphocarrier protein NPr (nitrogen related HPr). (90 aa)    
Predicted Functional Partners:
ptsP
Phosphoenolpyruvate-protein phosphotransferase PtsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr); Belongs to the PEP-utilizing enzyme family.
  
 
 0.992
ptsN
Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component).
 
 
 0.987
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.953
fruA
PTS system, fructose-specific IIBC component.
 
  
 0.927
manX
PTS system, mannose-specific IIAB component (EIIAB-MAN) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-MAN).
   
 
 0.882
rapZ
RNase adapter protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.857
plu0585
Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein.
  
 
 0.753
fruB
PTS system, fructose-specific IIA/FPr component.
 
 
 
 0.725
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.677
ptsH
Phosphocarrier protein HPr (Histidine-containing protein).
  
     0.666
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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