Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tldDTldD protein, suppresses the inhibitory activity of the carbon storage regulator (CSRA). (481 aa)    
Predicted Functional Partners:
pmbA
PmbA protein, involved in the maturation of antibiotic.
 
 
0.909
plu4066
Unnamed protein product; Similar to unknown protein YhdP of Escherichia coli.
     
 0.865
plu4065
Unnamed protein product; Similar to carbon-nitrogen hydrolase.
  
    0.858
plu4068
dTTP/UTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.739
plu4062
Barstar domain-containing protein; Unnamed protein product; Similar to ribonuclease inhibitor (barstar).
       0.679
csrA
Carbon storage regulator homolog; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
      
 0.675
cafA
Ribonuclease G (RNase G) (cytoplasmic axial filament protein).
       0.668
plu1526
Oxidored_FMN domain-containing protein; Unnamed protein product; Similar to oxidoreductase (N-ethylmaleimide reductase, nemA gene product of Escherichia coli and morphinone reductase).
      
 0.658
plu4063
Ribonuclease; Unnamed protein product; Similar to ribonuclease precursor (Barnase) (RNase Ba).
       0.657
mreD
Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
 
     0.617
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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