Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mreDRod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (162 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.990
plu4068
dTTP/UTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.890
plu1375
Cytoskeleton protein RodZ; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.
 
  
 0.855
minC
Septum site-determining protein (cell division inhibitor MinC); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.837
plu4066
Unnamed protein product; Similar to unknown protein YhdP of Escherichia coli.
     0.825
mreB
Rod shape-determining protein MreB.
  
  
 0.791
ftsQ
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
  
 0.726
plu1378
TPR_21 domain-containing protein; Unnamed protein product; Similar to unknown protein YfgM of Escherichia coli.
  
     0.725
ftsL
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
   
 0.719
minD
Septum site-determining protein (cell division inhibitor MinD).
  
  
 0.717
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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