| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISPlu4B | plu4077 | plu4082 | plu4077 | Transposase, IS4 family. | Unnamed protein product; Some similarities with unknown protein. | 0.773 |
| ISPlu4B | plu4078 | plu4082 | plu4078 | Transposase, IS4 family. | Unnamed protein product; Similar to putative transferase protein. | 0.773 |
| ISPlu4B | plu4079 | plu4082 | plu4079 | Transposase, IS4 family. | Unnamed protein product; Sone similarities in the N-terminal region with dehydrogenase. | 0.773 |
| ISPlu4B | plu4080 | plu4082 | plu4080 | Transposase, IS4 family. | Unnamed protein product; Unknown protein with two candidate membrane-spanning segments. | 0.773 |
| ISPlu4B | plu4081 | plu4082 | plu4081 | Transposase, IS4 family. | Pyruvate carboxyltransferase domain-containing protein; Unnamed protein product; Similar in the N-terminal region with aldolase. | 0.773 |
| ilvC | ilvD | plu4668 | plu4682 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 0.995 |
| ilvC | leuC | plu4668 | plu3675 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.797 |
| ilvC | leuD | plu4668 | plu3676 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.841 |
| ilvC | plu4079 | plu4668 | plu4079 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Unnamed protein product; Sone similarities in the N-terminal region with dehydrogenase. | 0.809 |
| ilvC | plu4081 | plu4668 | plu4081 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Pyruvate carboxyltransferase domain-containing protein; Unnamed protein product; Similar in the N-terminal region with aldolase. | 0.750 |
| ilvD | ilvC | plu4682 | plu4668 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.995 |
| ilvD | leuC | plu4682 | plu3675 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.899 |
| ilvD | leuD | plu4682 | plu3676 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.894 |
| ilvD | plu4079 | plu4682 | plu4079 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | Unnamed protein product; Sone similarities in the N-terminal region with dehydrogenase. | 0.781 |
| ilvD | plu4081 | plu4682 | plu4081 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | Pyruvate carboxyltransferase domain-containing protein; Unnamed protein product; Similar in the N-terminal region with aldolase. | 0.729 |
| leuC | ilvC | plu3675 | plu4668 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.797 |
| leuC | ilvD | plu3675 | plu4682 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 0.899 |
| leuC | leuD | plu3675 | plu3676 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
| leuC | plu4079 | plu3675 | plu4079 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Unnamed protein product; Sone similarities in the N-terminal region with dehydrogenase. | 0.878 |
| leuC | plu4081 | plu3675 | plu4081 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Pyruvate carboxyltransferase domain-containing protein; Unnamed protein product; Similar in the N-terminal region with aldolase. | 0.722 |
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