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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu4083Unnamed protein product; Hypothetical gene. (57 aa)    
Predicted Functional Partners:
plu4079
Unnamed protein product; Sone similarities in the N-terminal region with dehydrogenase.
  
 
 0.838
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.703
plu4084
Bcr/CflA family efflux transporter; Unnamed protein product; Similar to putative transport protein and multidrug resistance protein like bicyclomycin resistance protein.
       0.689
ilvD
Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family.
  
  
 0.649
leuB
3-isopropylmalate dehydrogenase (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
  
 
 0.613
thrA
Aspartokinase I-homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.603
metL
Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.603
ilvH
Acetolactate synthase isozyme III small subunit (AHAS-III) (acetohydroxy-acid synthase III small subunit) (ALS-III).
  
  
 0.602
plu1869
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family.
  
  
 0.599
plu1870
Aconitase_C domain-containing protein; Unnamed protein product; Similar to 3-isopropylmalate dehydratase, small subunit (leuD-2); Belongs to the LeuD family.
  
  
 0.599
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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