Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu4145Unnamed protein product; Some similarities with ABC-type transport protein (IM-ABC type). (617 aa)    
Predicted Functional Partners:
plu4143
Unnamed protein product; Some similarities with agmatinase SpeB (Agmatine ureohydrolase) (AUH); Belongs to the arginase family.
       0.773
plu4144
JmjC domain-containing protein; Unnamed protein product; Some similarities with unknown eucaryotic protein.
       0.773
plu4146
Unnamed protein product; Hypothetical protein.
       0.773
dnaK
Chaperone protein (heat shock protein 70) (heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.760
plu2469
ABC transporter domain-containing protein; Unnamed protein product; Similar to N-terminal region of ATP-binding component of ABC transporter.
  
 
  0.743
plu0571
Unnamed protein product; Similar to putative AAA-family ATPase gene.
  
 
  0.716
thrS
threonyl-tRNA synthetase (threonine--tRNA ligase); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
   0.640
hscA
Chaperone protein hscA (Hsc66); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.
  
  0.635
dnaJ
Heat shock protein dnaJ (HSP40) (chaperone protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...]
  
 
 
 0.566
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
 
 0.552
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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