Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu4259Unnamed protein product; Similar to glutathione S-transferase; Belongs to the GST superfamily. (207 aa)    
Predicted Functional Partners:
plu4258
Unnamed protein product; Similar to 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component HpaB.
     
 0.728
plu4232
Unnamed protein product; Similar to monooxygenase.
  
   
 0.612
gloA
Lactoylglutathione lyase (methylglyoxalase) (S-D-lactolyglutathione methylglyoxal lyase); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
  
 0.544
rpoZ
DNA-directed RNA polymerase omega chain (transcriptase omega chain) (RNA polymerase omega subunit); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 0.537
plu2242
DAO domain-containing protein; Unnamed protein product; Highly similar to probable D-amino acid oxidase.
      
 0.532
rpoC
RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.488
adhC
Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
   
 0.480
lysS
Lysyl-tRNA synthetase (Lysine--tRNA ligase); Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  0.465
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.456
gloB
Hydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
 
   0.454
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.