| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hsdM | hsdR | plu4319 | plu4322 | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.990 |
| hsdM | hsdS | plu4319 | plu4320 | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | Type I restriction enzyme specificity protein HsdS. | 0.991 |
| hsdM | plu0137 | plu4319 | plu0137 | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | Unnamed protein product; Highly similar to unknown protein. | 0.736 |
| hsdM | plu0598 | plu4319 | plu0598 | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | AAA_15 domain-containing protein; Unnamed protein product; Weakly similar to unknown protein. | 0.687 |
| hsdM | prrC | plu4319 | plu4321 | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | Anticodon nuclease PrrC. | 0.798 |
| hsdR | hsdM | plu4322 | plu4319 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | 0.990 |
| hsdR | hsdS | plu4322 | plu4320 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction enzyme specificity protein HsdS. | 0.976 |
| hsdR | lrp | plu4322 | plu1600 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Leucine-responsive regulatory protein. | 0.526 |
| hsdR | plu0137 | plu4322 | plu0137 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Unnamed protein product; Highly similar to unknown protein. | 0.732 |
| hsdR | plu0233 | plu4322 | plu0233 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | N6_Mtase domain-containing protein; Unnamed protein product; Similar to unknown protein and some weak similarities with deoxyribonuclease/methylase. | 0.788 |
| hsdR | plu0598 | plu4322 | plu0598 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | AAA_15 domain-containing protein; Unnamed protein product; Weakly similar to unknown protein. | 0.761 |
| hsdR | plu1158 | plu4322 | plu1158 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Unnamed protein product; Similar to unknown protein STY4592 of Salmonella enterica subsp. enterica serovar Typhi. | 0.822 |
| hsdR | plu1163 | plu4322 | plu1163 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | N6_Mtase domain-containing protein; Unnamed protein product; Some similarities with unknown protein. | 0.788 |
| hsdR | prrC | plu4322 | plu4321 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Anticodon nuclease PrrC. | 0.798 |
| hsdR | recA | plu4322 | plu1249 | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.613 |
| hsdS | hsdM | plu4320 | plu4319 | Type I restriction enzyme specificity protein HsdS. | Type I site-specific deoxyribonuclease HsdM; Truncated gene. Similar to the central region of integrase. | 0.991 |
| hsdS | hsdR | plu4320 | plu4322 | Type I restriction enzyme specificity protein HsdS. | Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.976 |
| hsdS | plu0137 | plu4320 | plu0137 | Type I restriction enzyme specificity protein HsdS. | Unnamed protein product; Highly similar to unknown protein. | 0.722 |
| hsdS | plu0233 | plu4320 | plu0233 | Type I restriction enzyme specificity protein HsdS. | N6_Mtase domain-containing protein; Unnamed protein product; Similar to unknown protein and some weak similarities with deoxyribonuclease/methylase. | 0.858 |
| hsdS | plu0598 | plu4320 | plu0598 | Type I restriction enzyme specificity protein HsdS. | AAA_15 domain-containing protein; Unnamed protein product; Weakly similar to unknown protein. | 0.871 |