| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cpxA | dsbA | plu4795 | plu0381 | Two-component sensor kinase. | Disulfide interchange protein DsbA precursor. | 0.494 |
| cpxA | holD | plu4795 | plu4251 | Two-component sensor kinase. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.678 |
| cpxA | plu0245 | plu4795 | plu0245 | Two-component sensor kinase. | Unnamed protein product; Similar to putative exported protein YicH of Escherichia coli. | 0.649 |
| cpxA | plu1752 | plu4795 | plu1752 | Two-component sensor kinase. | Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family. | 0.620 |
| cpxA | plu4369 | plu4795 | plu4369 | Two-component sensor kinase. | Unnamed protein product; Similar to bacteriophage tail fiber assembly protein. | 0.590 |
| cpxA | uspA | plu4795 | plu0121 | Two-component sensor kinase. | Universal stress protein A; Required for resistance to DNA-damaging agents. | 0.557 |
| cpxA | zapB | plu4795 | plu4766 | Two-component sensor kinase. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.564 |
| dsbA | cpxA | plu0381 | plu4795 | Disulfide interchange protein DsbA precursor. | Two-component sensor kinase. | 0.494 |
| dsbA | ftsN | plu0381 | plu4761 | Disulfide interchange protein DsbA precursor. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.770 |
| dsbA | holD | plu0381 | plu4251 | Disulfide interchange protein DsbA precursor. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.718 |
| dsbA | plu0245 | plu0381 | plu0245 | Disulfide interchange protein DsbA precursor. | Unnamed protein product; Similar to putative exported protein YicH of Escherichia coli. | 0.748 |
| dsbA | plu1752 | plu0381 | plu1752 | Disulfide interchange protein DsbA precursor. | Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family. | 0.667 |
| dsbA | plu4369 | plu0381 | plu4369 | Disulfide interchange protein DsbA precursor. | Unnamed protein product; Similar to bacteriophage tail fiber assembly protein. | 0.610 |
| dsbA | uspA | plu0381 | plu0121 | Disulfide interchange protein DsbA precursor. | Universal stress protein A; Required for resistance to DNA-damaging agents. | 0.638 |
| dsbA | zapB | plu0381 | plu4766 | Disulfide interchange protein DsbA precursor. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.748 |
| ftsN | dsbA | plu4761 | plu0381 | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Disulfide interchange protein DsbA precursor. | 0.770 |
| ftsN | holD | plu4761 | plu4251 | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.772 |
| ftsN | plu0245 | plu4761 | plu0245 | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unnamed protein product; Similar to putative exported protein YicH of Escherichia coli. | 0.669 |
| ftsN | plu1752 | plu4761 | plu1752 | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family. | 0.679 |
| ftsN | plu4369 | plu4761 | plu4369 | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unnamed protein product; Similar to bacteriophage tail fiber assembly protein. | 0.565 |