Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. (172 aa)    
Predicted Functional Partners:
ubiA
4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
    
 0.990
menF
Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
     
 0.912
pheA
P-protein [includes: chorismate mutase (CM); prephenate dehydratase (PDT)].
    
 0.849
tyrA
T-protein [includes: chorismate mutase (CM); prephenate dehydrogenase (PDH)].
    
 0.834
trpE
Anthranilate synthase component I.
    
 0.814
plu0570
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
    
 0.812
aroC
Chorismate synthase (EC 4.6.1.4) (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.810
aspC
Aspartate aminotransferase (transaminase A).
     
 0.805
tyrB
Aromatic-amino-acid aminotransferase (AROAT) (ARAT).
     
 0.805
trpG
Anthranilate synthase component II (Glutamine amido-transferase).
    
  0.802
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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