STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase (GPI) (phosphoglucoseisomerase) (PGI) (phosphohexose isomerase) (PHI). (548 aa)    
Predicted Functional Partners:
pfkA
6-phosphofructokinase isozyme I (phosphofructokinase-1) (phosphohexokinase-1); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.986
pgm
Phosphoglucomutase.
 
 0.985
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.984
eno
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.976
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.976
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.969
zwf
Glucose-6-phosphate 1-dehydrogenase (G6PD); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.969
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 
 0.945
manA
Mannose-6-phosphate isomerase (phosphomannose isomerase) (phosphohexomutase) (PMI).
 
 
 0.945
pykF
Pyruvate kinase I (PK-1); Belongs to the pyruvate kinase family.
  
 
 0.945
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.