Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemGProtoporphyrinogen oxidase (PPO). (178 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase (protoheme ferro-lyase) (heme synthetase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.948
hemF
Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
     
 0.945
hemN
Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.920
trkH
Trk system potassium uptake protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
       0.836
plu4400
Unnamed protein product; Similar to unknown protein YigZ of Escherichia coli.
       0.784
pepQ
Xaa-Pro dipeptidase (X-Pro dipeptidase) (proline dipeptidase) (prolidase) (imidodipeptidase); Splits dipeptides with a prolyl residue in the C-terminal position.
       0.743
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
       0.511
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
     
 0.494
cyaA
Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family.
  
     0.453
fadA
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
       0.414
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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