| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| deaD | plu4452 | plu4523 | plu4452 | Inducible ATP-independent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Unnamed protein product; Similar to ATP-dependent DNA helicase. | 0.946 |
| deaD | recQ | plu4523 | plu4620 | Inducible ATP-independent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | ATP-dependent DNA helicase RecQ. | 0.928 |
| mutL | plu1037 | plu4583 | plu1037 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | 0.417 |
| mutL | plu4452 | plu4583 | plu4452 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Unnamed protein product; Similar to ATP-dependent DNA helicase. | 0.788 |
| mutL | polA | plu4583 | plu0386 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.889 |
| mutL | recA | plu4583 | plu1249 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.592 |
| mutL | recQ | plu4583 | plu4620 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | ATP-dependent DNA helicase RecQ. | 0.715 |
| mutL | topA | plu4583 | plu2435 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...] | 0.501 |
| mutL | xni | plu4583 | plu0660 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Exodeoxyribonuclease IX (5'-3' exonuclease); Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.792 |
| plu1037 | mutL | plu1037 | plu4583 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.417 |
| plu1037 | plu4452 | plu1037 | plu4452 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | Unnamed protein product; Similar to ATP-dependent DNA helicase. | 0.897 |
| plu1037 | polA | plu1037 | plu0386 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.604 |
| plu1037 | recA | plu1037 | plu1249 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.648 |
| plu1037 | recQ | plu1037 | plu4620 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | ATP-dependent DNA helicase RecQ. | 0.923 |
| plu1037 | sbcD | plu1037 | plu3912 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | Nuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.481 |
| plu1037 | topA | plu1037 | plu2435 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...] | 0.530 |
| plu1037 | xni | plu1037 | plu0660 | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | Exodeoxyribonuclease IX (5'-3' exonuclease); Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.570 |
| plu4452 | deaD | plu4452 | plu4523 | Unnamed protein product; Similar to ATP-dependent DNA helicase. | Inducible ATP-independent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.946 |
| plu4452 | mutL | plu4452 | plu4583 | Unnamed protein product; Similar to ATP-dependent DNA helicase. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.788 |
| plu4452 | plu1037 | plu4452 | plu1037 | Unnamed protein product; Similar to ATP-dependent DNA helicase. | Toprim domain-containing protein; Unnamed protein product; Similar to DNA topoisomerase III. | 0.897 |
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