Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu4453Unnamed protein product; Similar to a putative DNA processing protein. (473 aa)    
Predicted Functional Partners:
plu4452
Unnamed protein product; Similar to ATP-dependent DNA helicase.
 
 0.981
plu1629
Lactamase_B domain-containing protein; Unnamed protein product; Similar to probable membrane protein YcaI of Escherichia coli.
 
  
 0.679
plu0199
Pribosyltran domain-containing protein; Unnamed protein product; Similar to unknown protein YhgH of Escherichia coli.
  
 
 0.538
plu1186
Peptidase_A24 domain-containing protein; Unnamed protein product; Similar to type IV prepilin peptidase; Belongs to the peptidase A24 family.
  
  
 0.491
plu1733
Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.491
pilU
PilU protein; Similar to prepilin peptidase PilU protein.
  
  
 0.487
recJ
Single-stranded-DNA-specific exonuclease RecJ.
 
   
 0.470
plu4451
AAA_12 domain-containing protein; Unnamed protein product; Some weak similarities with DNA helicase related protein.
       0.470
topA
DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
     
 0.455
phoA
Alkaline phosphatase precursor (APASE); Belongs to the alkaline phosphatase family.
  
    0.451
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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