Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
argIOrnithine carbamoyltransferase chain I (OTCase-1); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (338 aa)    
Predicted Functional Partners:
plu4567
Argininosuccinate synthase; Unnamed protein product; Similar to argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.978
argG
Argininosuccinate synthase (citrulline-aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.978
carB
Carbamoylphosphate synthetase large subunit; Belongs to the CarB family.
 
 
 0.975
argE
Acetylornithine deacetylase (acetylornithinase) (AO) (N-acetylornithinase) (NAO); Belongs to the peptidase M20A family. ArgE subfamily.
 
 
 0.966
argA
Amino-acid acetyltransferase (N-acetylglutamate synthase); Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.961
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.960
carA
Carbamoyl-phosphate synthase (glutamine-hydrolyzing); Belongs to the CarA family.
  
 
 0.957
argH
Argininosuccinate lyase (arginosuccinase) (ASAL).
  
  
 0.948
pyrB
Aspartate carbamoyltransferase catalytic chain (aspartate transcarbamylase) (ATCase); Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
0.943
plu4566
Unnamed protein product; Some similarities with unknown protein.
    
 0.909
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (42%) [HD]