Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase class II (fumarase); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.994
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.977
plu3138
Citrate synthase; Unnamed protein product; Weakly similar to citrate synthase.
  
 0.977
prpC
2-methylcitrate synthase (Methylcitrate synthase) (Citrate synthase 2); Belongs to the citrate synthase family.
  
 0.977
maeB
NADP-dependent malic enzyme (NADP-ME).
  
 0.975
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family.
 
 0.962
icd
Isocitrate dehydrogenase [NADP].
  
 0.949
ppc
Phosphoenolpyruvate carboxylase (PEPCASE) (PEPC); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.947
aceB
Malate synthase A (MSA).
   
 0.936
aspC
Aspartate aminotransferase (transaminase A).
   
 0.934
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.