close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu4563ATP-grasp domain-containing protein; Unnamed protein product; Some similarities with unknown protein. (436 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase (glutamine-hydrolyzing); Belongs to the CarA family.
  
 
 0.932
pyrE
Orotate phosphoribosyltransferase (OPRT) (OPRTASE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.794
fre
NAD(P)H-flavin reductase (NAD(P)H:flavin oxidoreductase).
  
 
 0.787
pyrF
Orotidine-5'-phosphate decarboxylase (OMP decarboxylase); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.782
pyrB
Aspartate carbamoyltransferase catalytic chain (aspartate transcarbamylase) (ATCase); Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.782
plu4564
Unnamed protein product; Some similarities with multidrug resistance proteins.
       0.777
plu4567
Argininosuccinate synthase; Unnamed protein product; Similar to argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.777
plu4568
PALP domain-containing protein; Unnamed protein product; Similar to cystathionine beta-synthase (cysteine synthase).
   
 
 0.734
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.703
plu0247
Unnamed protein product; Highly similar to xanthine/uracil permease family protein YicE of Escherichia coli.
  
  
 0.698
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (34%) [HD]