STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
plu4567Argininosuccinate synthase; Unnamed protein product; Similar to argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (396 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase (arginosuccinase) (ASAL).
 
 
 0.997
argI
Ornithine carbamoyltransferase chain I (OTCase-1); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.978
argE
Acetylornithine deacetylase (acetylornithinase) (AO) (N-acetylornithinase) (NAO); Belongs to the peptidase M20A family. ArgE subfamily.
  
 0.975
carB
Carbamoylphosphate synthetase large subunit; Belongs to the CarB family.
 
 0.933
argG
Argininosuccinate synthase (citrulline-aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 
0.923
argB
Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
  
 0.918
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.917
purA1
Adenylosuccinate synthetase 1; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
 0.915
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (ADSS) (AMPSASE); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
 0.915
aspC
Aspartate aminotransferase (transaminase A).
   
 
 0.908
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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