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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu4568PALP domain-containing protein; Unnamed protein product; Similar to cystathionine beta-synthase (cysteine synthase). (342 aa)    
Predicted Functional Partners:
plu2021
Serine acetyltransferase; Unnamed protein product; Some similarities with serine O-acetyltransferase.
 
 0.873
cysE
Serine acetyltransferase (SAT).
 
 0.870
cysS
cysteinyl-tRNA synthetase (cysteine--tRNA ligase) (CysRS); Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.850
plu4567
Argininosuccinate synthase; Unnamed protein product; Similar to argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.783
plu4566
Unnamed protein product; Some similarities with unknown protein.
       0.777
plu4565
Unnamed protein product; Similar to nodulation protein.
       0.770
plu4563
ATP-grasp domain-containing protein; Unnamed protein product; Some similarities with unknown protein.
   
 
 0.734
mtnA
MTA/SAH nucleosidase [Includes: 5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine ac [...]
  
  
 0.608
luxS
Autoinducer-2 (AI-2) production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
 0.605
plu0523
Unnamed protein product; Similar to cystathionine gamma-lyase.
 
 
 0.547
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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