| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsH | hflC | plu4535 | plu4578 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | 0.909 |
| ftsH | hflK | plu4535 | plu4579 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | 0.934 |
| ftsH | hflX | plu4535 | plu4580 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.453 |
| ftsH | hfq | plu4535 | plu4581 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.446 |
| ftsH | miaA | plu4535 | plu4582 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.448 |
| ftsH | nuoC | plu4535 | plu3087 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.491 |
| ftsH | tig | plu4535 | plu3870 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Trigger factor (TF) (chaperone); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.506 |
| ftsH | yidC | plu4535 | plu4906 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.538 |
| hflC | ftsH | plu4578 | plu4535 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.909 |
| hflC | hflK | plu4578 | plu4579 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | 0.997 |
| hflC | hflX | plu4578 | plu4580 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.766 |
| hflC | hfq | plu4578 | plu4581 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.574 |
| hflC | miaA | plu4578 | plu4582 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.588 |
| hflC | nuoC | plu4578 | plu3087 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.516 |
| hflC | plu4457 | plu4578 | plu4457 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | AAA domain-containing protein; Truncated gene. Some similarities with the N-terminal region of unknown protein. | 0.476 |
| hflC | purA | plu4578 | plu4577 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | Adenylosuccinate synthetase (IMP--aspartate ligase) (ADSS) (AMPSASE); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.526 |
| hflC | yidC | plu4578 | plu4906 | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.531 |
| hflK | ftsH | plu4579 | plu4535 | Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.934 |
| hflK | hflC | plu4579 | plu4578 | Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | Lambda CII stability-governing protein HflC; HflC and HflK could regulate a protease. | 0.997 |
| hflK | hflX | plu4579 | plu4580 | Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.886 |