Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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btuBVitamin B12 receptor precursor protein BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (619 aa)    
Predicted Functional Partners:
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.873
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.848
plu3512
TonB_C domain-containing protein; Unnamed protein product; Some similarities with energy transducer TonB. Putative secreted protein.
 
 
 
 0.693
plu2717
TonB_C domain-containing protein; Unnamed protein product; Similar to unknown protein CjrB of Escherichia coli O164 and some similarities with inner-membrane protein TonB.
   
 
 0.643
ompA
Outer membrane protein A precursor (Outer membrane protein II*); Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.615
btuF
Vitamin B12 transport protein BtuF precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
   
 0.614
lamB
Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.
  
  
 0.597
trmA
tRNA (Uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
     
 0.567
plu1752
Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family.
    
 0.561
plu1423
Unnamed protein product; Similar to unknown protein YbfA of Escherichia coli.
  
     0.551
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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