Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cytRTranscriptional repressor. (342 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain).
    
 
 0.693
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.580
hfq
Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
      
 0.546
plu0758
Unnamed protein product; Similar to multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.540
plu0759
HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.540
mdtA
Multidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.540
acrR
acrAB operon repressor.
      
 0.540
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
    
 
 0.461
bvgS
Virulence sensor protein BvgS precursor.
    
 
 0.441
hsdR
Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.
   
  
 0.436
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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