Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpFGlycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (276 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase (ATP:glycerol 3-phosphotransferase) (glycerokinase) (GK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 
 0.990
glpQ
Glycerophosphoryl diester phosphodiesterase, periplasmic precursor (glycerophosphodiester phosphodiesterase).
  
 
 0.893
glpD
Aerobic glycerol-3-phosphate dehydrogenase GlpD; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.862
plu1041
Unnamed protein product; Weakly similar to serine/threonine phosphoprotein phosphatase.
    
   0.582
plu2353
Hist_deacetyl domain-containing protein; Unnamed protein product; Highly similar to probable acetylpolyamine aminohydrolase.
    
   0.578
fruA
PTS system, fructose-specific IIBC component.
  
   
 0.565
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.511
plu2403
NDK domain-containing protein; Truncated gene. Highly similar to C-terminal region of transposase; Belongs to the NDK family.
  
 
 0.511
dnaJ
Heat shock protein dnaJ (HSP40) (chaperone protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...]
    
 
 0.502
plu3369
ANK_REP_REGION domain-containing protein; Unnamed protein product; Some similarities with phospholipase A accessory protein.
    
 0.502
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (42%) [HD]