Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
pfkA6-phosphofructokinase isozyme I (phosphofructokinase-1) (phosphohexokinase-1); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase (GPI) (phosphoglucoseisomerase) (PGI) (phosphohexose isomerase) (PHI).
  
 0.985
gatY
Tagatose-bisphosphate aldolase GatY.
 
 
 0.958
fba
Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.950
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family.
  
  
 0.945
fbp
Fructose-1,6-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (FBPase).
    
 0.937
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.934
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.930
manA
Mannose-6-phosphate isomerase (phosphomannose isomerase) (phosphohexomutase) (PMI).
    
 0.914
agaZ
Putative tagatose 6-phosphate kinase agaZ.
     
 0.913
fbaB
Fructose-biphosphate aldolase class I (FBP aldolase).
    
 0.913
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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