Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfaQLipopolysaccharide core biosynthesis glycosyl transferase RfaQ. (354 aa)    
Predicted Functional Partners:
rfaG
Lipopolysaccharide core biosynthesis protein RfaG (Glucosyltransferase I).
 
 
 0.998
kdtA
3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
 0.979
rfaF
ADP-heptose--LPS heptosyltransferase II.
 
 
0.976
rfaC
Lipopolysaccharide heptosyltransferase-1.
 
  
0.961
plu0452
Unnamed protein product; Similar to lipopolysaccharide 1,6-galactosyltransferase (UDP-D-galactose--(Glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosyltransferase), RfaB protein of Escherichia coli.
  
 
 0.945
walO
WalO protein; Some similarities with lipopolysaccharide biosynthesis protein.
  
  
 
0.928
rfaL
O-antigen ligase RfaL.
  
 
 0.924
walW
WalW protein; Similar to putative glycosyltransferase.
 
  
 0.908
nuoC
NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.896
rfaE
ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
   
 0.790
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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