Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfaLO-antigen ligase RfaL. (408 aa)    
Predicted Functional Partners:
rfaC
Lipopolysaccharide heptosyltransferase-1.
  
 
 0.932
rfaF
ADP-heptose--LPS heptosyltransferase II.
  
 
 0.931
rfaG
Lipopolysaccharide core biosynthesis protein RfaG (Glucosyltransferase I).
  
 
 0.931
rfaQ
Lipopolysaccharide core biosynthesis glycosyl transferase RfaQ.
  
 
 0.924
plu0452
Unnamed protein product; Similar to lipopolysaccharide 1,6-galactosyltransferase (UDP-D-galactose--(Glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosyltransferase), RfaB protein of Escherichia coli.
  
 
 0.921
kdtA
3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
    
 0.918
wzc
Tyrosine-protein kinase Wzc.
  
  
 0.723
mutM
formamidopyrimidine-DNA glycosylase (FAPY-DNA glycosylase); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.551
wblF
WblF protein; Similar to putative glycosyl transferase.
  
  
 0.524
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
  
 0.488
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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