Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ldhL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (320 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.987
pgiB
Glucose-6-phosphate isomerase.
  
 0.978
tktA
Transketolase; Belongs to the transketolase family.
  
 0.865
dnaK
Molecular chaperone DnaK; Belongs to the heat shock protein 70 family.
  
 0.857
lonA
Heat shock ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  0.844
atpA1
ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 0.825
atpA2
ATP synthase subunit A.
  
 0.825
atpA
ATP synthase subunit A.
  
 0.825
prsA
Phosphoribosylpyrophosphate synthetase.
  
 0.823
ACF07186.1
Acyl carrier protein, putative.
  
 
 0.815
Your Current Organism:
Mycoplasma arthritidis
NCBI taxonomy Id: 243272
Other names: M. arthritidis 158L3-1, Mycoplasma arthritidis 158L3-1, Mycoplasma arthritidis str. 158L3-1, Mycoplasma arthritidis strain 158L3-1
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