STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_207Identified by similarity to EGAD:57314; match to protein family HMM PF00149; match to protein family HMM TIGR00040; Belongs to the metallophosphoesterase superfamily. YfcE family. (167 aa)    
Predicted Functional Partners:
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.803
MG_109
Serine/threonine protein kinase, putative; MG109 has 1 transmembrane region; identified by similarity to GB:AAL58474.1; match to protein family HMM PF00069; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
     
 0.787
MG_108
Protein phosphatase 2C, putative; Identified by similarity to EGAD:57254; match to protein family HMM PF00481.
  
  
 0.757
MG_246
Identified by similarity to PDB:1T71_A; match to protein family HMM PF00149; match to protein family HMM TIGR00282.
      
 0.750
MG_328
Conserved hypothetical protein; MG328 has 5 M protein repeats. These short repeats are found in multiple copies in bacterial M proteins. The M proteins bind to IgA and are closely associated with virulence; identified by similarity to EGAD:57085.
      
 0.740
MG_208
Glycoprotease family protein; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57160; match to protein family HMM PF00814.
     
 0.658
pdp
Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
      
 0.645
MG_281
Conserved hypothetical protein; MG281 has 1 transmembrane region; identified by similarity to EGAD:57033.
      
 0.602
hrcA
Heat-inducible transcription repressor HrcA, putative; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.564
hmw3
HMW3 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism (By similarity).
  
  
 0.480
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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