STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_281Conserved hypothetical protein; MG281 has 1 transmembrane region; identified by similarity to EGAD:57033. (556 aa)    
Predicted Functional Partners:
MG_328
Conserved hypothetical protein; MG328 has 5 M protein repeats. These short repeats are found in multiple copies in bacterial M proteins. The M proteins bind to IgA and are closely associated with virulence; identified by similarity to EGAD:57085.
      
 0.729
MG_389
Conserved hypothetical protein; MG389 has 1 transmembrane region; identified by similarity to EGAD:57010.
      
 0.685
MG_220
Conserved hypothetical protein; MG220 has 1 transmembrane region; identified by similarity to EGAD:57057.
      
 0.663
pdp
Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
      
 0.641
MG_207
Identified by similarity to EGAD:57314; match to protein family HMM PF00149; match to protein family HMM TIGR00040; Belongs to the metallophosphoesterase superfamily. YfcE family.
      
 0.602
MG_279
Expressed protein of unknown function; MG279 has 2 transmembrane regions. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57048.
       0.594
MG_280
Conserved hypothetical protein; MG280 has 2 transmembrane regions; identified by similarity to EGAD:57038.
       0.594
MG_428
MG428, which has features of a LuxR bacterial regulatory protein, is not essential for growth in SP-4 (Glass, et al., 2005); identified by similarity to EGAD:56778.
      
 0.584
MG_208
Glycoprotease family protein; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57160; match to protein family HMM PF00814.
      
 0.582
MG_390
ABC transporter, ATP-binding/permease protein; MG390 has 4 transmembrane regions, plus and ATP binding domain, and a peptidase domain. There is no predicted substrate binding protein or other ABC transporter component in the vicinity; identified by similarity to GB:AAA03343.1; match to protein family HMM PF00005; match to protein family HMM PF03412.
      
 0.556
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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