STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptaPhosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651. (320 aa)    
Predicted Functional Partners:
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.996
pdhC
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
  
 
 0.956
pgk
Phosphoglycerate kinase; Identified by similarity to SP:P36204; match to protein family HMM PF00162.
  
  
 0.858
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
  
  
 0.829
manB
Phosphoglucomutase/phosphomannomutase, putative; Identified by similarity to EGAD:56902; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; Belongs to the phosphohexose mutase family.
     
 0.804
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
     
 0.706
ptsG
PTS system, glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
  
  
 0.687
pgi
Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342.
  
 
 0.646
MG_303
Metal ion ABC transporter, ATP-binding protein, putative; MG303 is part of an ABC transporter cassette comprised of MG302-MG303-MG304. There is no predicted substrate binding protein in the vicinity. MG302, the permease, is similar to cobalt transport proteins; identified by similarity to OMNI:NTL01BC0131; match to protein family HMM PF00005.
  
    0.645
MG_304
Metal ion ABC transporter, ATP binding protein, putative; MG304 is part of an ABC transporter cassette comprised of MG302-MG303-MG304. There is no predicted substrate binding protein in the vicinity. MG302, the permease, is similar to cobalt transport proteins; identified by similarity to OMNI:NTL01BC0130; match to protein family HMM PF00005.
  
    0.645
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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