STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_309Lipoprotein, putative; MG309 is a lipoprotein with 1 transmembrane region; identified by similarity to EGAD:57195; Belongs to the MG307/MG309/MG338 family. (1225 aa)    
Predicted Functional Partners:
MG_307
Lipoprotein, putative; Identified by similarity to EGAD:56878.
     
0.838
MG_308
ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to EGAD:57201; match to protein family HMM PF00270; match to protein family HMM PF00271.
       0.774
MG_306
Membrane protein, putative; MG306 has 7 transmembrane regions; identified by similarity to EGAD:56882.
       0.773
MG_185
Lipoprotein, putative; Identified by similarity to EGAD:36928; match to protein family HMM PF03202; match to protein family HMM PF03305.
      
 0.750
mgpA
MgPa adhesin; The protein is the major adhesin mediating the attachment of this mycoplasma to the ciliated epithelium.
      
 0.750
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
      
 0.750
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.641
MG_310
Hydrolase, alpha/beta fold family; MG310 belongs to the SwissProt lipase/esterase LIP3/bchO family; however the similarity to characterized lipase/esterases is weak, even with the Mycoplasma mycoides triplet of lipase/esterases (PMID: 7789792); identified by similarity to EGAD:57198; match to protein family HMM PF00561.
       0.559
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
       0.545
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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