STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_354Conserved hypothetical protein; MG354 has 1 transmembrane region; identified by similarity to EGAD:56836. (137 aa)    
Predicted Functional Partners:
nusB
MG027 was recently shown to encode a protein with structural similarity to NusB. Liu, J. et al. 2004 'A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to nusb proteins' Proteins 55:1082-6; identified by similarity to EGAD:56746.
      
 0.750
p37
Phosphonate ABC transporter, substrate binding protein (P37), putative; P37 is part of a high-affinity transport system.
      
 0.683
MG_353
DNA-binding protein HU, putative; Identified by similarity to GB:AAK52476.1.
       0.524
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Belongs to the FKBP-type PPIase family. Tig subfamily.
   
  
 0.516
MG_366
Conserved hypothetical protein; Identified by similarity to EGAD:57141.
      
 0.420
MG_369
The DAKS domain is the predicted phosphatase domain of the dihydroxyacetone kinase family; identified by similarity to EGAD:57129; match to protein family HMM PF02734.
      
 0.400
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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