STRINGSTRING
nnr protein (Thermotoga maritima) - STRING interaction network
"nnr" - Bifunctional NAD(P)H-hydrate repair enzyme Nnr in Thermotoga maritima
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrBifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity); In the N-terminal section; belongs to the NnrE/AIBP family (498 aa)    
Predicted Functional Partners:
Tmari_0472
Nicotinamidase; Derived by automated computational analysis using gene prediction method- Protein Homology (174 aa)
   
        0.999
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5’-terminal phosphate and a 3’-terminal hydroxyl group (By similarity) (165 aa)
   
        0.914
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (313 aa)
              0.898
Tmari_0921
OsmC/Ohr family protein; Derived by automated computational analysis using gene prediction method- Protein Homology (138 aa)
              0.895
Tmari_0923
Soluble lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method- Protein Homology (154 aa)
              0.888
Tmari_1852
Maltodextrin glucosidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glycosyl hydrolase 13 family (674 aa)
   
        0.887
Tmari_0925
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (377 aa)
              0.885
Tmari_0922
Alcohol dehydrogenase, iron-containing; Derived by automated computational analysis using gene prediction method- Protein Homology (359 aa)
              0.883
Tmari_0926
Radical activating enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (286 aa)
              0.854
Tmari_0920
Methyl-accepting chemotaxis protein; Derived by automated computational analysis using gene prediction method- Protein Homology (661 aa)
              0.842
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (17%) [HD]