TM_0006 protein (Thermotoga maritima) - STRING interaction network

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TM_0006

Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His. (345 aa)

Predicted Functional Partners:

TM_0007

0.889

TM_0005

0.787

TM_0008

0.584

TM_0796

0.491

TM_0068

0.433

dapA

0.433

Your Current Organism:

Thermotoga maritima

NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TM_0005	TM_0006	TM_0005	TM_0006	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.787
TM_0005	TM_0007	TM_0005	TM_0007	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	Hypothetical protein; Identified by sequence similarity; putative.	0.787
TM_0005	TM_0008	TM_0005	TM_0008	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	0.578
TM_0006	TM_0005	TM_0006	TM_0005	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	0.787
TM_0006	TM_0007	TM_0006	TM_0007	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	Hypothetical protein; Identified by sequence similarity; putative.	0.889
TM_0006	TM_0008	TM_0006	TM_0008	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	0.584
TM_0006	TM_0068	TM_0006	TM_0068	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	D-mannonate oxidoreductase, putative; Similar to GP:1736838 percent identity: 50.90; identified by sequence similarity; putative.	0.433
TM_0006	TM_0796	TM_0006	TM_0796	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 54.55; identified by sequence similarity; putative.	0.491
TM_0006	dapA	TM_0006	TM_1521	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.433
TM_0007	TM_0005	TM_0007	TM_0005	Hypothetical protein; Identified by sequence similarity; putative.	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	0.787
TM_0007	TM_0006	TM_0007	TM_0006	Hypothetical protein; Identified by sequence similarity; putative.	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.889
TM_0007	TM_0008	TM_0007	TM_0008	Hypothetical protein; Identified by sequence similarity; putative.	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	0.584
TM_0008	TM_0005	TM_0008	TM_0005	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.	0.578
TM_0008	TM_0006	TM_0008	TM_0006	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.584
TM_0008	TM_0007	TM_0008	TM_0007	Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative.	Hypothetical protein; Identified by sequence similarity; putative.	0.584
TM_0068	TM_0006	TM_0068	TM_0006	D-mannonate oxidoreductase, putative; Similar to GP:1736838 percent identity: 50.90; identified by sequence similarity; putative.	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.433
TM_0796	TM_0006	TM_0796	TM_0006	Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 54.55; identified by sequence similarity; putative.	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.491
dapA	TM_0006	TM_1521	TM_0006	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.	0.433

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