STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0008Conserved hypothetical protein; Similar to GB:L42023 SP:P44095 PID:1006233 PID:1221130 PID:1205266 percent identity: 55.96; identified by sequence similarity; putative. (224 aa)    
Predicted Functional Partners:
TM_0006
Muconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.
       0.584
TM_0007
Hypothetical protein; Identified by sequence similarity; putative.
       0.584
TM_0005
DNA helicase, putative; Similar to GB:AE000782 percent identity: 77.56; identified by sequence similarity; putative.
       0.578
TM_0305
Endoglucanase, putative; Similar to GP:3560020 percent identity: 55.11; identified by sequence similarity; putative.
  
     0.495
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
    
  0.492
TM_1426
Fe-hydrogenase, subunit alpha; Similar to GP:2865517 percent identity: 100.00; identified by sequence similarity; putative.
    
  0.492
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
  0.410
TM_1227
Endo-1,4-beta-mannosidase; Similar to PID:1679597 percent identity: 54.44; identified by sequence similarity; putative.
  
     0.407
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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