Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_0014Methyl-accepting chemotaxis protein, putative; Similar to PID:1197391 GB:AE000512 percent identity: 99.64; identified by sequence similarity; putative. (278 aa)    
Predicted Functional Partners:
cheA
Chemotaxis sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
 
 0.985
TM_0718
Purine-binding chemotaxis protein; Similar to GB:M13462 SP:P07365 PID:145520 GB:U00096 PID:1736540 percent identity: 61.43; identified by sequence similarity; putative.
 
 0.903
cheW
Purine-binding chemotaxis protein; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
 
 0.901
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.865
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.857
TM_0013
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 70.52; identified by sequence similarity; putative.
       0.811
cheD
Chemotaxis methylation protein; Deamidates glutamine residues on chemoreceptors (MCPs). CheD- mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase. In addition, demethylates methylated glutamate residues on chemoreceptors Mcp2 and Mcp4. Enhances the activity of CheC.
 
  0.734
porC
Pyruvate ferredoxin oxidoreductase, gamma subunit; Similar to PID:2052278 GB:AE000512 percent identity: 99.53; identified by sequence similarity; putative.
       0.559
porD
Pyruvate ferredoxin oxidoreductase, delta subunit; Similar to GP:1197392 percent identity: 100.00; identified by sequence similarity; putative.
       0.538
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit; Similar to GP:2052279 percent identity: 100.00; identified by sequence similarity; putative.
       0.538
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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