Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
porDPyruvate ferredoxin oxidoreductase, delta subunit; Similar to GP:1197392 percent identity: 100.00; identified by sequence similarity; putative. (101 aa)    
Predicted Functional Partners:
porC
Pyruvate ferredoxin oxidoreductase, gamma subunit; Similar to PID:2052278 GB:AE000512 percent identity: 99.53; identified by sequence similarity; putative.
 0.999
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit; Similar to GP:2052279 percent identity: 100.00; identified by sequence similarity; putative.
 
 0.999
porB
Pyruvate ferredoxin oxidoreductase, beta subunit; Similar to PID:1197393 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 
 0.999
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
  
 0.998
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
    
 0.988
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.984
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
    
 0.978
pta
Phosphate butyryltransferase; In addition to acetyl-CoA (100%), the enzyme accepts propionyl-CoA (60%) and butyryl-CoA (30%); Belongs to the phosphate acetyltransferase and butyryltransferase family.
     
 0.977
TM_0396
Iron-sulfur cluster-binding protein; Similar to GB:AE000782 percent identity: 64.67; identified by sequence similarity; putative.
    
 0.960
pyk
Pyruvate kinase; Similar to GB:AL009126 percent identity: 64.53; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
    
 0.959
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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