STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_00386-pyruvoyl tetrahydrobiopterin synthase, putative; Similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 percent identity: 62.18; identified by sequence similarity; putative. (120 aa)    
Predicted Functional Partners:
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
 
  
 0.996
TM_0156
Alkaline phosphatase; Similar to SP:P19405 GB:M33634 PID:551721 PID:1945090 GB:AL009126 percent identity: 58.53; identified by sequence similarity; putative; Belongs to the alkaline phosphatase family.
     
  0.954
TM_0384
Anaerobic ribonucleoside-triphosphate reductase-related protein; Similar to SP:P07075 PID:15354 percent identity: 53.92; identified by sequence similarity; putative.
  
 
 0.937
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.871
TM_0040
Dihydropteroate synthase; Similar to GB:D26185 SP:P28822 GB:M34053 PID:143410 PID:467466 percent identity: 68.63; identified by sequence similarity; putative.
    
 0.865
TM_1171
Transcriptional regulator, crp family; Similar to GB:Z26044 SP:P47200 PID:398391 percent identity: 50.56; identified by sequence similarity; putative.
   
  0.792
TM_0035
Hypothetical protein; Identified by sequence similarity; putative.
       0.765
TM_0036
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
       0.765
TM_0037
Conserved hypothetical protein; Similar to PID:558266 percent identity: 57.38; identified by sequence similarity; putative.
       0.765
TM_0041
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26185 SP:P29252 PID:467468 GB:AL009126 percent identity: 65.87; identified by sequence similarity; putative.
     
 0.663
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.