STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (259 aa)    
Predicted Functional Partners:
TM_0038
6-pyruvoyl tetrahydrobiopterin synthase, putative; Similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 percent identity: 62.18; identified by sequence similarity; putative.
 
  
 0.999
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.997
TM_0041
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26185 SP:P29252 PID:467468 GB:AL009126 percent identity: 65.87; identified by sequence similarity; putative.
    
 0.967
TM_0385
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 52.27; identified by sequence similarity; putative.
  
  
  0.940
pyk
Pyruvate kinase; Similar to GB:AL009126 percent identity: 64.53; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
    
  0.930
TM_0040
Dihydropteroate synthase; Similar to GB:D26185 SP:P28822 GB:M34053 PID:143410 PID:467466 percent identity: 68.63; identified by sequence similarity; putative.
    
 0.855
TM_0037
Conserved hypothetical protein; Similar to PID:558266 percent identity: 57.38; identified by sequence similarity; putative.
    
  0.783
TM_0035
Hypothetical protein; Identified by sequence similarity; putative.
       0.767
TM_0036
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
       0.767
TM_0034
Iron-sulfur cluster-binding protein; Similar to GP:2622960 percent identity: 62.36; identified by sequence similarity; putative.
       0.575
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.