STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0040Dihydropteroate synthase; Similar to GB:D26185 SP:P28822 GB:M34053 PID:143410 PID:467466 percent identity: 68.63; identified by sequence similarity; putative. (278 aa)    
Predicted Functional Partners:
TM_0041
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26185 SP:P29252 PID:467468 GB:AL009126 percent identity: 65.87; identified by sequence similarity; putative.
 
 0.999
TM_0166
Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GB:L04520 SP:Q05865 PID:142936 PID:1119198 GB:AL009126 percent identity: 57.76; identified by sequence similarity; putative; Belongs to the folylpolyglutamate synthase family.
 
 0.999
TM_1679
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 58.19; identified by sequence similarity; putative.
     
  0.954
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.872
TM_0038
6-pyruvoyl tetrahydrobiopterin synthase, putative; Similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 percent identity: 62.18; identified by sequence similarity; putative.
    
 0.865
TM_0035
Hypothetical protein; Identified by sequence similarity; putative.
       0.765
TM_0036
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
       0.765
TM_0037
Conserved hypothetical protein; Similar to PID:558266 percent identity: 57.38; identified by sequence similarity; putative.
       0.765
trpGD
Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 
  
 0.696
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 
 0.680
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.