STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0053Esterase, putative; Similar to PID:1708751 percent identity: 57.35; identified by sequence similarity; putative. (364 aa)    
Predicted Functional Partners:
TM_0051
iron(II) transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
   
   0.827
TM_0050
iron(II) transport protein A; Similar to SP:P33649 PID:414746 PID:606343 GB:U00096 PID:1789812 percent identity: 63.79; identified by sequence similarity; putative.
     
 0.817
TM_0052
Hypothetical protein; Identified by sequence similarity; putative.
       0.813
TM_0054
Hypothetical protein; Identified by sequence similarity; putative.
       0.781
TM_0049
Iron-sulfur cluster-binding protein; Similar to GB:AE000666 percent identity: 56.54; identified by sequence similarity; putative.
    
  0.610
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
  
 0.599
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
     
 0.537
TM_0703
Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family.
    
  0.535
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  0.529
trpGD
Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
  
 
 0.527
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.