STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uxaCUronate isomerase, putative; Similar to SP:P42607 PID:606033 GB:U00096 PID:2367192 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. (451 aa)    
Predicted Functional Partners:
TM_0068
D-mannonate oxidoreductase, putative; Similar to GP:1736838 percent identity: 50.90; identified by sequence similarity; putative.
 
 
 0.997
TM_0440
Hypothetical protein; Identified by sequence similarity; putative.
 
  
 0.986
uxuA
D-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.983
TM_1062
Beta-glucuronidase; Similar to PID:642973 PID:14446 PID:412358 percent identity: 57.73; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.974
iolO
D-tagatose 3-epimerase-related protein; Catalyzes the reversible epimerization between 5-keto-L- gluconate (5-dehydro-L-gluconate) and D-tagaturonate, and thus probably functions in a myo-inositol degradation pathway together with IolG, IolM and IolN. Is not active on the enantiomer 5- keto-D-gluconate. Was also shown to be a nonphosphorylated sugar isomerase with broad substrate specificity in vitro. Is able to catalyze the reversible C3- epimerization of L-ribulose to L-xylulose, D-ribulose to D-xylulose, D- psicose to D-fructose, and D-tagatose to D-sorbose, with a substrate prefere [...]
    
  0.880
TM_0281
alpha-L-arabinofuranosidase; Similar to SP:P94531 PID:1770022 PID:1913931 GB:AL009126 percent identity: 58.66; identified by sequence similarity; putative.
   
 
 0.838
TM_0063
Hypothetical protein; Identified by sequence similarity; putative.
     
 0.788
TM_0067
2-keto-3-deoxygluconate kinase; Similar to PID:1146189 SP:P50845 GB:AL009126 percent identity: 47.39; identified by sequence similarity; putative.
 
   
 0.701
TM_0437
exo-poly-alpha-D-galacturonosidase, putative; Similar to GB:M31308 SP:P15922 PID:148447 percent identity: 49.48; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 28 family.
 
  
 0.677
TM_0065
Transcriptional regulator, IclR family; Similar to SP:P37728 GB:X62072 PID:48982 percent identity: 59.13; identified by sequence similarity; putative.
     
 0.632
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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