STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuAD-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (360 aa)    
Predicted Functional Partners:
TM_0068
D-mannonate oxidoreductase, putative; Similar to GP:1736838 percent identity: 50.90; identified by sequence similarity; putative.
 
 0.999
TM_0067
2-keto-3-deoxygluconate kinase; Similar to PID:1146189 SP:P50845 GB:AL009126 percent identity: 47.39; identified by sequence similarity; putative.
 
  
 0.993
uxaC
Uronate isomerase, putative; Similar to SP:P42607 PID:606033 GB:U00096 PID:2367192 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
 
  
 0.984
TM_1080
Sugar-phosphate isomerase; Similar to GB:AE000657 percent identity: 77.62; identified by sequence similarity; putative.
   
 
  0.931
TM_0066
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Similar to PID:1146190 SP:P50846 GB:AL009126 percent identity: 67.42; identified by sequence similarity; putative.
     
 0.855
TM_0065
Transcriptional regulator, IclR family; Similar to SP:P37728 GB:X62072 PID:48982 percent identity: 59.13; identified by sequence similarity; putative.
     
 0.632
aguA
Alpha-glucuronidase; Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. It catalyzes the cleavage of alpha-(1->2)-glycosidic bond of the 4-O-methyl-D-glucuronic acid side chain of xylan and releases 4-O-methylglucuronic acid from xylan. Belongs to the glycosyl hydrolase 67 family.
   
 0.565
TM_0063
Hypothetical protein; Identified by sequence similarity; putative.
     
 0.473
TM_0441
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:AE000782 percent identity: 62.88; identified by sequence similarity; putative.
 
 
 0.457
TM_0439
Transcriptional regulator, GntR family; Similar to GB:AL009126 percent identity: 58.29; identified by sequence similarity; putative.
 
   
 0.436
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.