Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fliWConserved hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (149 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.996
TM_0082
Flagellar hook-associated protein 3; Similar to SP:P96501 PID:1762339 GB:AL009126 percent identity: 56.38; identified by sequence similarity; putative.
 
 
 0.975
TM_0083
Flagellar hook-associated protein 1; Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 49.92; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
 
  
 0.951
TM_1124
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 73.75; identified by sequence similarity; putative.
 
  
 0.888
TM_0758
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.866
TM_0132
Flagellin, putative; Similar to SP:Q05203 PID:216262 percent identity: 56.44; identified by sequence similarity; putative.
 
 
 0.855
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheX chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
 
  
 0.852
fliD
Flagellar hook-associated protein 2, putative; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
  
 0.818
TM_1179
Flagellar protein FliS; Similar to GB:M85241 SP:P26609 GB:X52093 PID:153987 percent identity: 56.80; identified by sequence similarity; putative.
 
  
 0.817
TM_0085
Hypothetical protein; Identified by sequence similarity; putative.
  
  
 0.768
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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