STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0094General secretion pathway protein F, putative; Similar to GB:AE000657 percent identity: 58.04; identified by sequence similarity; putative. (399 aa)    
Predicted Functional Partners:
TM_0837
General secretion pathway protein E; Similar to GB:AE000657 percent identity: 67.38; identified by sequence similarity; putative.
 
 0.995
TM_1271
Type IV pilin-related protein; Similar to SP:P35646 GB:Z12609 PID:41331 percent identity: 54.22; identified by sequence similarity; putative.
 
  
 0.963
TM_0088
comE protein, putative; Similar to SP:P31772 GB:L42023 PID:1003754 PID:1222365 PID:148874 percent identity: 65.23; identified by sequence similarity; putative; Belongs to the bacterial secretin family.
 
 
 0.947
TM_1696
Type IV prepilin peptidase; Similar to GB:AE000657 percent identity: 61.90; identified by sequence similarity; putative.
 
  
 0.911
TM_1362
Motility protein PilT; Similar to GB:AE000657 percent identity: 66.67; identified by sequence similarity; putative.
  
 0.865
TM_0093
Hypothetical protein; Identified by sequence similarity; putative.
       0.810
TM_0095
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 55.12; identified by sequence similarity; putative.
       0.810
TM_0096
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.791
obg
Conserved hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.790
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.787
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.