STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0102Basic membrane protein; Similar to GB:L24194 GB:L35050 PID:508421 PID:516592 PID:1753225 percent identity: 56.65; identified by sequence similarity; putative. (359 aa)    
Predicted Functional Partners:
TM_0103
Sugar ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 70.26; identified by sequence similarity; putative.
 
 0.998
TM_0105
Sugar ABC transporter, permease protein; Similar to GB:AE000782 percent identity: 63.76; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.997
TM_0104
Sugar ABC transporter, permease protein; Similar to GB:AE000782 percent identity: 59.01; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.996
TM_0101
Hypothetical protein; Identified by sequence similarity; putative.
       0.827
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.603
obg
Conserved hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
    0.592
TM_0096
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.582
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.580
TM_0099
Hypothetical protein; Identified by sequence similarity; putative.
       0.580
TM_0093
Hypothetical protein; Identified by sequence similarity; putative.
       0.561
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.